The
four cycles any drug goes through in the body are absorption, distribution,
metabolism and elimination. Any combination of drugs as well as certain herbs
can result in either a pharmacokinetic or a pharmacodynamic interaction at any
of these four stages. Such interactions are very difficult to study, because it
is not simply the combination of two compounds that can lead to an interaction
but also the timing, concentration or even the preparation of the food or the
compound that can result in an interaction. Genetic factors can also contribute
as certain people may act on herbs differently when they are taken into the
body.
One
risk
of drug interactions is perhaps if ingested
together with alcohol, they lose their effectiveness. Not only will you not be
getting better, but often you will become sicker with nausea, vomiting,
headaches, shortness of breath and possibly convulsions. It isn't just alcohol
that should be avoided while taking Rhodiola herb. Sometimes you have to avoid
milk also. This specific is definitely legitimate of the tetracycline types of
prescription.
Among
the types of drugs known to have interactions with the Rhodiola herb are
anti-seizure medications, antidepressants, tranquilizers and calcium channel
blockers. Some reports conclude that this interaction only occurs if the
Rhodiola herb is consumed at the same time as the drug. Consuming the Rhodiola
herb well before or well after the consumption the drug may not cause an
interaction. Because the chemical involved in this interaction is unknown, this
risk is associated with whole Rhodiola herb leaves, Rhodiola herb roots and
even Rhodiola herb powder.
When
combined with diabetes medication Rhodiola
herb can cause a dangerous decrease in blood sugar levels. Large doses can also
thin the blood and in effect amplify the effects of blood thinning drugs like
warfare and aspirin or other blood thinners.
Rhodiola
herb is contraindicated during pregnancy-especially in the first
trimester-because of the effects of anthraquinone glycosides found in the roots
of Rhodiola herb plants. It is also contraindicated in patients who are
hypersensitive to the herb or related plant species.
Be
Alert of herb interactions that results to Poisoning caused by atropine
contamination of some commercial Rhodiola herbs can occur. Signs and symptoms
of toxicity include blurred vision, dilated pupils, and rapid pulse rate. Treatment
of this, if needed, includes physostigmine reversal.
Combinations
of individual nutrients can also lead to interactions. When combined with iron
and Rhodiola herb, zinc absorption can be reduced or the zinc can reduce the
absorption of the iron and the Rhodiola herb. The effects of this type of
interaction can take days, weeks or even months to display, making it very
difficult to diagnose
Another
drug interaction with a very common food involves using the herb with the
grapefruit. Containing many nutrients including vitamin C and a long list of
phytochemicals, an unidentified phytochemicals in grapefruit leads to a
Pharmacodynamic interaction that amplifies be a fact of certain drugs and
therefore increases the risk of drug toxicity as well as drug side
effects.
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